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EyeMelanoma.org

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  • Home
  • About
  • Organizations
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    • Diagnosis and Treatment
    • Research Opportunities
    • Clinical Trials Search
  • Support
    • Financial Assistance
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    • Patient Empowerment
    • Vision-Related Support
  • Conferences
  • Videos
  • Articles
    • Recent Journal Articles
    • How to Journal Search

OCULAR MELANOMA CLINICAL TRIALS

On this page, you will find:


  • The ClinicalTrials.gov Database Link — to search for trials to discuss with your medical team


  • Educational and Support Resources for Using ClinicalTrials.gov


  • Important Information About Participating in Any Clinical Trial


  • Expanded Access (Compassionate Use) Information

Ocular Melanoma Clinical Trials Search

ClinicalTrials.gov Database

About Clinical Trials.gov:

  • "ClinicalTrials.gov is a [free] website and online database of clinical research studies and information about their results."
  • "The U.S. National Library of Medicine maintains the website, and it includes studies that take place in all 50 states and over 200 countries."
  • "The study sponsor or investigator is responsible for the safety, science, and accuracy of any study they list on ClinicalTrials.gov. They are also responsible for ensuring that their study follows all relevant laws and regulations."


Click on the link below to go directly to their database to begin your search.

Search for Ocular Melanoma Trials at ClinicalTrials.gov

Assistance When Using ClinicalTrials.gov

Detailed Guidance from ClinicalTrials.gov

Detailed Guidance from ClinicalTrials.gov

Detailed Guidance from ClinicalTrials.gov

Filling Out the Search Fields/Filters and Understanding Results:


Instructions from ClinicalTrials.gov:

  • Quick guide to searching for clinical studies
  • Questions to ask before you search
  • Detailed guide to searching for clinical studies
  • Special instructions for using certain search filters 


How to Read a Study Record

Once you have found a clinical trial of interest, ClinicalTrials.gov provides "detailed guidance on how to read the information in clinical study records."


Glossary of Common Terms from ClinicalTrials.gov will help you understand words and phrases frequently used in search fields and results. [The U.S. FDA provides explanations of additional clinical trial-related words and phrases not included in the above.]

Tips from EyeMelanoma.org

Detailed Guidance from ClinicalTrials.gov

Detailed Guidance from ClinicalTrials.gov

Using the "Condition/Disease" Field When Searching ClinicalTrials.gov:


1) To get started, look at search results using the term Ocular Melanoma to broadly describe the tumor. Then:


a) If the tumor is in the uvea, search again using Uveal Melanoma (which will automatically search for its synonym intraocular melanoma at the same time), and then try again as a separate search using the specific part of the uvea — Choroidal Melanoma, Iris Melanoma, or Ciliary Body Melanoma. 


b) If the tumor is in the conjunctiva, use Conjunctival Melanoma. 


Important Note: You will get a different number of search results depending on which term above you choose to use in the "Condition/Disease" field. Therefore, it is strongly recommended to always conduct multiple relevant searches.

Support from National Cancer Institute

Detailed Guidance from ClinicalTrials.gov

Support from National Cancer Institute

Accessing Phone, Online Chat, and Email Support During Search:


"NCI's Cancer Information Service can help answer your cancer-related questions whether you are a patient, family or friend, health care provider, or researcher. CIS is a free and confidential service. Our trained information specialists provide personalized responses to a range of cancer topics, including finding cancer treatment, cancer research, and clinical trials."

1-800-422-6237 [toll free], Monday through Friday 9 a.m. – 9 p.m. Eastern Standard Time. Both phone support and one-on-one online chats are available during these hours. (This service is also available in Spanish.)


Steps to Help Your Search

"Step 2" provides important information about the different types of clinical trial databases — maintained by the U.S. government, cancer centers, drug and biotech companies, and clinical trial listing/matching services — in NCI's "Steps to Find a Clinical Trial." 

Information About Participating in a Clinical Trial

Clinical Trial Guides for Patients

Clinical Trial Guides for Patients

Clinical Trial Guides for Patients

From American Cancer Society

Topics include:

  • "Questions to Ask Yourself Before Joining"
  • "Risks vs. Benefits"
  • "Common Concerns About Clinical Trials"


From National Cancer Institute

Topics include:

  • "Why Participate in a Clinical Trial?" 
  • "Are Clinical Trials Safe?
  • "Who Pays for Clinical Trials?"

 (Also available in Spanish.)


From U.S. Department of Health and Human Services

Topics include:

  • "Questions to Ask About Volunteering for a Research Study"
  • "Regulations That Protect Research Volunteers" 

(Also available in Spanish.)

Clinical Trial Videos for Patients

Clinical Trial Guides for Patients

Clinical Trial Guides for Patients

From Global Resource for Advancing Cancer Education

"Clinical Trials 101"

(Presenter: Dr. Maria Velez; July 2025)

5-part video series (approx. 5 minutes each):

•  "Enrolling and Starting Treatment"

•  "What to Expect in Phase I Trials"

•  "What to Expect in Phase II Trials"

•  "What to Expect in Phase III Trials"

•  "Clinical Trials Myths and FAQs"

Expanded Access (Compassionate Use)

U.S. Food and Drug Administration's Information on Expanded Access and Other Treatment Options

U.S. Food and Drug Administration's Information on Expanded Access and Other Treatment Options

U.S. Food and Drug Administration's Information on Expanded Access and Other Treatment Options

 "When a patient does not respond to current approved treatments for a variety of reasons, other options still may be available. For serious and life-threatening illnesses, some patients may want to talk to their healthcare provider about (1) trying an investigational drug through a clinical trial, expanded access, or right to try, or (2) trying an approved drug that is used for a different purpose than what is listed on the FDA-approved drug label (known as off-label use)." Click on the 'Learn More' link below for more detailed information provided by the FDA. 


(Also: American Cancer Society provides information on "expanded access programs and the Right to Try Act.")

Learn More

How to Find "Expanded Access Availability" on ClinicalTrials.gov

U.S. Food and Drug Administration's Information on Expanded Access and Other Treatment Options

U.S. Food and Drug Administration's Information on Expanded Access and Other Treatment Options

Search Tips From EyeMelanoma.org:

1) The first step is to fill in the "Condition/Disease" field, the first entry listed in the ClinicalTrials.gov database's "Focus Your Search" box. Use "Ocular Melanoma" as a start. Then hit the search button. The search results will now appear. 

2) Next, find the "Expanded Access" option in the "Focus Your Search" box/column on the left side of the results page. (This option is displayed as the last item in the "Study Status" section near the top.) Then, click on the plus sign next to the "Expanded Access" words to open up further filter choices. Click on the "Available" button as the filter and select "Apply Filters" to see the results that show the currently available treatments for expanded access use that have been entered into the database.

Note: Tips for additional "condition/disease" search words for you to try can be found above in the first section of this EyeMelanoma.org webpage.

New information added to this webpage: August 6, 2025

 All content and links to external sites re-verified on this webpage: July 25, 2025  

Any Feedback? Please Email: Erica@EyeMelanoma.org  

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  • About
  • Organizations
  • Doctors
  • Diagnosis and Treatment
  • Research Opportunities
  • Clinical Trials Search
  • Financial Assistance
  • Personal Support
  • Mental Health Support
  • Patient Empowerment
  • Vision-Related Support
  • Conferences
  • Videos
  • Recent Journal Articles
  • How to Journal Search

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Focus Area: Ocular Melanoma Eye Cancer — Both Uveal Melanoma and Conjunctival Melanoma.
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