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Before searching for ocular melanoma clinical trials in any database, please be advised by the National Cancer Institute that "there are many lists of cancer clinical trials taking place in the United States. [...] Because of the many types of sponsors, no single list [database] contains every clinical trial."
Learn about these different types of clinical trial databases — maintained by the U.S. government, cancer centers, drug and biotech companies, and clinical trial listing/matching services — in NCI's "Steps to Find a Clinical Trial."
"ClinicalTrials.gov, a [free] resource provided by the U.S. National Library of Medicine, is a registry and results information database of clinical research studies sponsored or funded by a broad range of public and private organizations around the world."
"Information is provided by study sponsors and investigators, and they are responsible for ensuring that the studies follow all applicable laws and regulations."
Filling Out the Search Fields and Understanding Results:
When Searching ClinicalTrials.gov:
Search results will frequently differ depending on which term is placed in the "condition/disease" field.
Phone, Online Chat, and Email Support During Search:
"NCI's Cancer Information Service provides accurate, up-to-date, and reliable information that is easy to understand and free of charge. Our trained information specialists provide personalized responses to a range of cancer questions, including tailored clinical trials searches." [Note: ClinicalTrials.gov includes in its database all of the NCI-supported clinical trials, which are those sponsored or otherwise financially supported by the National Cancer Institute.]
1-800-422-6237 [toll free], Monday through Friday 9 a.m. – 9 p.m. Eastern Standard Time. Both phone support and one-on-one online chats are available during these hours. This service is also available in Spanish.
From National Cancer Institute
Topics include "What Are Clinical Trials?," "Paying for Clinical Trials," "Patient Safety," and "Questions to Ask Your Doctor about Clinical Trials." Be sure to click on the "+" sign next to each topic in the left-hand column of the guide to view subtopics.
(Also available in Spanish.)
From American Cancer Society
ACS provides a printable list of "Questions to Ask Before Joining a Clinical Trial" and discusses "Risks vs. Benefits" and "Common Concerns About Clinical Trials."
You can find information about clinical trials coverage by private insurance, Medicaid, Medicare, Tricare, or VA in the "How to Pay for a Clinical Trial" link accessed at the bottom of their page. Separately, their database of health insurance laws by state includes laws relating to clinical trials.
From U.S. Department of Health and Human Services' Office for Human Research Protections
Resources include "Questions to Ask About Volunteering for a Research Study," "Regulations to Protect Research Volunteers," and "Short Videos About Participating in Human Research."
(Also available in Spanish.)
"Sometimes called 'compassionate use,' expanded access is a potential pathway for a patient with a serious or life-threatening disease or condition to try an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when there are no comparable or satisfactory therapies available. [...] There are times when it is not possible for a patient to be a part of a clinical trial. In those circumstances, expanded access may be the only way for a patient to receive an investigational medical product. The U.S. Food and Drug Administration is committed to increasing awareness about the expanded access process."
On the Advanced Search page of ClinicalTrials.gov:
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